ANALYSIS OF BENEFICIAL MICROORGANISMS IN KOMBUCHA AS ANTIMICROBIAL AGENTS AGAINST SKIN DISEASE-CAUSING MICROORGANISMS
DOI:
https://doi.org/10.71282/jurmie.v3i7.2378Keywords:
Antimicrobial, Kombucha, Microbiome, Propionibacterium acnes, Staphylococcus aureus.Abstract
Skin infections caused by pathogenic bacteria, such as Propionibacterium acnes and Staphylococcus aureus, remain a significant health concern, highlighting the need for natural antimicrobial alternatives to reduce the risk of antibiotic resistance. This study aimed to analyze the microorganisms present in kombucha and evaluate their antimicrobial potential against skin pathogenic bacteria based on previously published studies. A narrative literature review with a descriptive qualitative approach was conducted by collecting scientific articles from Google Scholar, ScienceDirect, and PubMed. The collected data were integrated and analyzed descriptively to describe the characteristics of kombucha microorganisms and their antimicrobial activity. The findings indicate that kombucha contains a Symbiotic Culture of Bacteria and Yeast (SCOBY), which is predominantly composed of acetic acid bacteria, lactic acid bacteria, and yeasts. During fermentation, these microorganisms produce various bioactive compounds, including acetic acid, gluconic acid, polyphenols, and flavonoids, which contribute to the inhibition of pathogenic bacterial growth. Previous studies also demonstrate that the antimicrobial activity of kombucha increases with longer fermentation periods, as indicated by the formation of inhibition zones against Propionibacterium acnes and Staphylococcus aureus. Based on these findings, kombucha has the potential to be developed as a natural antimicrobial ingredient in topical formulations for preventing bacterial skin infections.
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References
Asri, S., & Martina, A. (2018). Uji Aktivitas Antimikroba Kombucha Teh Hitam dan Kombucha Teh Kulit Manggis Berdasarkan Lama Fermentasi. Jurnal Mikologi Indonesia, 2(2), 67-76.
Effendi, F., Roswiem, A. P., & Stefani, E. (2014). Uji aktivitas antibakteri teh kombucha probiotik terhadap bakteri Escherichia coli dan Staphylococcus aureus. FITOFARMAKA: jurnal ilmiah farmasi, 4(2), 1-9.
Farza, K. (2025). Formulasi Sediaan Deodoran Spray dan Uji Aktivitas Antimikroba dari Ferementasi Kombucha Pucuk Merah (Syzygium myrtifplium Walp.) (Doctoral dissertation, Universitas Bhakti Kencana).
Hermanto, N. S., Sulistiarini, R., & Maulidya, V. (2025, October). Aktivitas Antibakteri Kombucha Kulit Kayu Kemiri (Aleurites moluccana) Terhadap Propionibacterium acnes Sebagai Dasar Pengembangan Perawatan Antijerawat: Antibacterial Activity of Candlenut Stem Bark (Aleurites moluccana) Kombucha Against Propionibacterium acnes as Development of Anti-Acne Skin Care. In Proceeding of Mulawarman Pharmaceuticals Conferences (Vol. 19, pp. 28-34). https://doi.org/10.30872/mpc.v19i.482
Joevanda, S., Salsabilla, N., Qiftiah, M., Sani K, F., Rusdi, M. S., & Efendi, M. R. (2024). Formulation of an Antibacterial Peel-Off Gel Mask from Kombucha Fermented with Gerga Orange Peel Infusion (Citrus x aurantium L.). Indonesian Journal of Pharmaceutical Education, 4(3), 461-472.
Khamidah, A., Antarlina, S. S., Pengkajian, B., Pertanian, T., & Timur, J. (2020). Peluang Minuman Kombucha Sebagai Pangan Fungsional Opportunities Of Kombucha Drinking As A Functional Food. Agrika: Jurnal Ilmu-Ilmu Pertanian, 14(2), 184-200.
Rahmawati, T. A., Junitasari, A., & Rosahdi, T. D. (2024, October). Uji aktivitas antibakteri streptococcus pyogenes terhadap sediaan sabun mandi cair kombucha berbasis ekstrak kulit buah manggis (Garcinia mangostana L.). In Gunung Djati Conference Series (Vol. 44, pp. 41-49).
Sari, I. P., Septiani, T., & Pujiastuti, Y. A. (2026). Pengaruh Variasi Sumber Karbon Dan Lama Fermentasi Terhadap Karakteristik Fisikokimia Kombucha Sari Nangka. Jurnal Sains dan Teknologi Pangan, 11(3). https://doi.org/10.63071/ezw0wv16
Sreeramulu, G., Zhu, Y., & Knol, W. (2000). Kombucha fermentation and its antimicrobial activity. Journal of agricultural and food chemistry, 48(6), 2589-2594.
Wungu, K. (2024). Kemampuan krim wajah dari ekstrak daun teh hijau (Camellia sinensis L.) sebagai antibakteri (propionibacterium acnes): studi in vitro dan in silico (Doctoral dissertation, Universitas Islam Negeri Maulana Malik Ibrahim).
Yan, J. H., Zheng, D. W., Gu, H. Y., Yu, Y. J., Zeng, J. Y., Chen, Q. W., ... & Zhang, X. Z. (2023). In Situ Sprayed Biotherapeutic Gel Containing Stable Microbial Communities for Efficient Anti‐Infection Treatment. Advanced Science, 10(4), 2205480. https://doi.org/10.1002/advs.202205480Digital Object Identifier (DOI)
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